Hormone Receptor Positive/HER2 Negative Breast Carcinoma: Association of <i>PIK3CA</i> Mutational Status with PD-L1 and Tumor Cell Microenvironment and Their Prognostic Significance.

Int J Mol Sci · 2025 · PMC12524508 · PMID 41096755

Europe PMC DOI

hedged sentences

0.0960

closest p · 1.9× alpha

0.0960

boldest claim

The sentences

a statistical trendp = 0.096so close (0.05 < p ≤ 0.1)

Also, a statistical trend was noticed in CD4 and PD-L1 distribution between these groups where tumors with high CD4 infiltrate and positive PD-L1 did not have metastasis/recurrence ( p = 0.096 and p = 0.065, respectively) ( Table 4 ).

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did not reach statistical significanceno p-value reported

All other survival analysis for DSS did not reach statistical significance in the PIK3CA non-mutated and mutated tumors ( Table 6 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Hormone Receptor Positive/HER2 Negative Breast Carcinoma: Association of &lt;i&gt;PIK3CA&lt;/i&gt; Mutational Status with PD-L1 and Tumor Cell Microenvironment and Their Prognostic Significance.

The sentences

Hormone Receptor Positive/HER2 Negative Breast Carcinoma: Association of <i>PIK3CA</i> Mutational Status with PD-L1 and Tumor Cell Microenvironment and Their Prognostic Significance.