Characterization of Steroid Metabolic Pathways in Established Human and Mouse Cell Models.

Int J Mol Sci · 2025 · PMC12525206 · PMID 41096985

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Under serum-free conditions in the presence of metformin, most steroids showed a trend towards decreased levels and the ratio of progesterone/pregnenolone, denoting 3βHSD2 activity, decreased ~2-fold ( Figure S2 ). 2.1.3.

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