Estimating the Contribution of Renal Function to Endothelial Dysfunction and Subclinical Inflammation with a Two-Cohort Study: Living Kidney Donors and Their Transplant Recipients.

Int J Mol Sci · 2025 · PMC12525258 · PMID 41096801

Europe PMC DOI

hedged sentences

0.0694

closest p · 1.4× alpha

0.0694

boldest claim

The sentences

approached significancep -value = 0.0694so close (0.05 < p ≤ 0.1)

In the recipient cohort, E-selectin (from 37 ± 19 to 34 ± 14 ng/mL; p -value = 0.0225) and PECAM-1 (from 79 ± 23 to 71 ± 15 ng/mL; p -value = 0.0016) decreased after transplantation while the reduction in vWF approached significance (from 181 ± 53 to 167 ± 57%; p -value = 0.0694).

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highly significantno p-value reported

Importantly, a highly significant change was observed for sTNFR1 and sTNFR2 in both cohorts.

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