Prospective multicenter validation of preoperative plasma ceramides as novel predictive biomarkers for clinically relevant post-hepatectomy liver failure.

In the external validation set, although the incidence of CR-PHLF was higher in the high-risk group than in the low-risk group across all subgroups, the difference did not reach statistical significance, except that in the HCC subgroups (Supplemental Digital Content Table S5, available at: http://links.lww.com/JS9/E487 ), which may be attributed to the limited sample size in the external validation set.

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