Relationship between serum ApoB-100 and lumbar bone mineral density in postmenopausal women: a retrospective analysis of a health screening population.

As illustrated, age-stratified analysis revealed that the negative correlation between ApoB-100 and BMD was more pronounced in younger postmenopausal women (<60 years) (β=-10.18, 95%CI: -13.94 to -6.42) compared to older women (≥60 years) (β=-2.93, 95%CI: -5.09 to -3.24), although the interaction association between groups did not reach statistical significance ( P interaction=0.152).

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BMI-stratified analysis demonstrated an increasing trend in the strength of the negative correlation between ApoB-100 and BMD with increasing BMI: normal weight (BMI<24 kg/m2) β=-4.25 (95%CI: -10.72 to -3.23), overweight (BMI 24–28 kg/m2) β=-7.51 (95%CI: -9.65 to -3.46), and obese (BMI≥28 kg/m2) β=-10.73 (95%CI: -15.31 to -0.86), though the interaction association of BMI was not significant ( P interaction=0.377).

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