Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.

Although it did not reach statistical significance, we observed that while there was an increase in the median of IgG anti-N in reinfected individuals, as previously reported for COVID-recovered cohorts ( 18 ), the antibody response against the Spike and the RBD did not change, with the exception of anti-RBD IgG2 and IgG4 that increased ( Figure 5 ).

also in 111,027 other papers