Prognostication in patients with idiopathic pulmonary fibrosis using quantitative airway analysis from HRCT: a retrospective study.

Specifically, SPAV and STotalAV were highly significant (p<0.0001) in the untreated group, while losing significance in treated patients (p>0.05).

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Given the high degree of collinearity between SSmallAV and STermAV in both cohorts, and the fact that each variable demonstrated independent or near-significant associations with mortality in multivariable analyses (SSmallAV: p=0.001 in OSIC; STermAV: p∼0.05 in both cohorts) ( table 2 ), we elected to combine them into a single metric, SPAV.

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