Structure-activity relationships of fenarimol analogues with potent in vitro and in vivo activity against Madurella mycetomatis, the main causative agent of mycetoma.

RSC Med Chem · 2025 · PMC12529582 · PMID 41113115

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showed a trendno p-value reported

mycetomatis hyphae in vitro , but less lipophilic compounds showed a trend to prolonged larval survival demonstrates that a balance of chemical properties is likely to be needed to penetrate the mycetoma grain and kill the pathogen.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Structure-activity relationships of fenarimol analogues with potent &lt;i&gt;in vitro&lt;/i&gt; and &lt;i&gt;in vivo&lt;/i&gt; activity against &lt;i&gt;Madurella mycetomatis&lt;/i&gt;, the main causative agent of mycetoma.

The sentences

Structure-activity relationships of fenarimol analogues with potent <i>in vitro</i> and <i>in vivo</i> activity against <i>Madurella mycetomatis</i>, the main causative agent of mycetoma.