Association of HbA1c/HDL-C ratio and depression with cardiometabolic multimorbidity in middle-aged and older adults: a nationwide prospective cohort study.

Front Nutr · 2025 · PMC12529971 · PMID 41112747

Europe PMC DOI

hedged sentence

0.4220

closest p · 8.4× alpha

0.4220

boldest claim

The sentences

failed to reach statistical significancep = 0.422not close (p > 0.1)

Similarly, in Supplementary Figure S2B , when the HbA1c/HDL-C ratio was tested as a mediator between depression and CMM, the indirect effect also failed to reach statistical significance (HR = 0.998, 95% CI: 0.992–1.004, p = 0.422).

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