Barely Significant
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Increased Mitochondrial Common Deletion in Oligo-Astheno-Teratozoospermia Samples Is Not Correlated with Increased Global DNA Methylation: Unexpected Results for ATP Levels.

Int J Fertil Steril · 2025 · PMC12530209 · PMID 41090429

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highly significantP<0.001actually significant
However, a highly significant difference in mtDNA4977 copy levels was observed between the OAT groups compared to the control groups (P<0.001).

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Although OAT patients exhibited a higher average methylation profile than the control group, the difference did not reach statistical significance, possibly because of the high variability observed within the OAT group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.