Barely Significant
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Association of estrogen receptor single nucleotide polymorphisms and perinatal depression.

PLoS One · 2025 · PMC12530586 · PMID 41100533

1
hedged sentence
0.0300
closest p · 0.6× alpha
0.0300
boldest claim

The sentences

nominally significantp = 0.03actually significant
Out of 56 SNPs analyzed, one SNP in the ESR1 gene (rs2982712) was nominally significantly associated with PND (OR 0.83, 95% CI 0.71–0.98, p = 0.03) as well as with persistent depression (OR 0.77, 95% CI 0.61–0.98, p = 0.03) in the overdominant model (DD/dd vs.

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