The mutational landscape and actionable targets of gallbladder cancer: an ancestry-informed and comparative analysis of a Chilean population.

Front Oncol · 2025 · PMC12531073 · PMID 41114336

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did not reach statistical significanceno p-value reported

Mutations in TP53 and KRAS seem to be mutually exclusive, although this trend did not reach statistical significance ( Figure 3 ). 3.3.

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highly significantno p-value reported

Notably, ATM, BRCA1, and BRCA2 mutations are highly significant due to their involvement in the DNA damage response (DDR) pathway.

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