Oligodendrogliomas, cyclin pathway after the introduction of the molecular 2021 World Health Organization (WHO) criteria.

In the analysis of Grade 2 oligodendrogliomas, the difference did not reach statistical significance (10.86 years versus 13.35 years).

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They considered p16 positive when at least 1% of tumour cells expressed p16 and found that the correlation was highly significant: 85% of patients with CDKN2A deletion had a loss of p16 expression.

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