Effects of weight control interventions on cardiovascular outcomes: an umbrella review of systematic reviews and meta-analyses.

Int J Obes (Lond) · 2025 · PMC12532613 · PMID 40715579

Europe PMC DOI

hedged sentence

0.8180

closest p · 16.4× alpha

0.8180

boldest claim

The sentences

showed a trendP = 0.818not close (p > 0.1)

While GLP-1 RAs showed a trend towards reducing all-cause mortality (OR = 0.90, 95% CI: 0.82–98, I 2 = 40%; moderate, IV) (Egger’s test P = 0.818), they significantly reduced the risk of CVD mortality (OR = 0.88, 95% CI: 0.70–97, I 2 = 18%; moderate, IV) (Egger’s test P = 0.624).

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