Spatial metabolomics reveals the effects of Acanthopanax senticosus on region-specific alterations in neurotransmitters and metabolites levels in the brains of α-syn transgenic Parkinson's disease model mice.

Metab Brain Dis · 2025 · PMC12532642 · PMID 41099888

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did not reach statistical significanceno p-value reported

Moreover, the level of 3-MT, a metabolite of DA produced by catechol-O-methyl-transferase (COMT), was elevated throughout the brains of mice in the ASH group, although this trend did not reach statistical significance.

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