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Intranasal delivery of DPSC-derived small extracellular vesicles-encased phloroglucinol attenuates non-motor and motor deficits and promotes neurogenesis in an in vivo rat model of Parkinson's disease.

Stem Cell Res Ther · 2025 · PMC12532972 · PMID 41102844

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showed a trendP < 0.001actually significant
The sEV-Phl treatment showed a trend of improvement in rotarod performance time starting from week 1 PMT, with significant differences observed at week 2 ( P < 0.001) and week 4 ( P < 0.005) compared to the corresponding MPTP group (Fig. 6 C).

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