Heart Failure and Stroke Risk in Atrial Fibrillation: Temporal Trends From a Nationwide Cohort Study.

Importantly, the magnitude of the IS risk related to HF decreased over time similarly across all analyses, although the interaction between HF and calendar‐year period did not reach statistical significance in analyses without OAC therapy ( P values for interaction: 0.003, 0.093, 0.021, and 0.152 in the 1‐year analysis with and without OAC therapy, and in the 2‐year analysis with and without OAC therapy, respectively; Figure 3 and Figure S4 ).

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