Impact of thyroid dysfunction on clinical outcome in head and neck cancer: a systematic review and meta-analysis.

BMC Cancer · 2025 · PMC12535142 · PMID 41107787

Europe PMC DOI

hedged sentence

0.0590

closest p · 1.2× alpha

0.0590

boldest claim

The sentences

did not reach statistical significanceP = 0.059so close (0.05 < p ≤ 0.1)

(2018) reported several findings related to PFS: comparing the overall hypothyroid cohort to the reference group yielded a Hazard Ratio suggesting potentially longer PFS, though this did not reach statistical significance (HR: 0.579, 95% CI: 0.329–1.022, P = 0.059).

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