Multimodal Brain Monitoring-Guided Anesthesia Management Improves Functional Connectivity, Enhances Recovery and Attenuates Postoperative Pain in Elderly Surgical Patients.

24 Previous studies have demonstrated that the fALFF values in the cuneus exhibit a decreasing trend, corresponding to cognitive function decline. 25 , 26 Our findings, which revealed that management guided by multimodal brain monitoring may effectively modulate regional neural activity in cognition-related brain regions, are consistent with those of previous studies.

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Although the primary outcome of this study, which is the difference of PND incidence between groups, did not reach statistical significance, we observed a numerical reduction in the incidence in the intervention group.

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