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Recent advances in multicomponent synthesis of 5-substituted 1<i>H</i>-tetrazoles from aldehydes: catalytic methods and green chemistry approaches.

RSC Adv · 2025 · PMC12536426 · PMID 41122386

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a strong trendno p-value reported
Electron-withdrawing groups (EWGs), such as nitro and halogens like chloro and bromo, generally result in higher yields, with a strong trend observed where the para -nitro group yields the highest at 90%.

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