Barely Significant
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A phenome-wide association study of genetically determined nicotine metabolism reveals novel links with health-related outcomes.

Eur J Epidemiol · 2025 · PMC12537601 · PMID 40646428

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a clear trendno p-value reported
The strongest associations, based on p-values, highlighted a clear trend: higher values of genetically determined ALT levels were consistently associated with a higher risk of hepatic diseases such as hepatitis, primary liver cancer and non-alcoholic cirrhosis.

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