borderline significantp = 0.06
The pooled analysis revealed a borderline significant 30% increased recurrence risk for ITCs versus node-negative disease (HR 1.3, 95% CI: 1.0–1.6; p = 0.06), with remarkable consistency between St Clair et al.
The pooled analysis revealed a borderline significant 30% increased recurrence risk for ITCs versus node-negative disease (HR 1.3, 95% CI: 1.0–1.6; p = 0.06), with remarkable consistency between St Clair et al.
Analysis of ITC studies ( 30 , 31 , 34 , 36 , 38 ) demonstrated mild funnel plot asymmetry, though Egger’s test did not reach statistical significance (intercept = 1.2, p = 0.18).