Monosodium Iodoacetate Induces Knee Osteoarthritis in Rats in a Dose- and Time-Dependent Manner.

J Pain Res · 2025 · PMC12539362 · PMID 41127857

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a clear trendno p-value reported

45 Our findings reveal a clear trend: compared with the 0.5 mg and 1.0 mg groups, the 1.5 mg and 2 mg MIA groups showed a significantly greater reduction in PWT and WBD beginning on day 3 after injection.

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an increasing trendno p-value reported

However, between day 7 and day 14 ( Figure 2B , d, p>0.05), PTW showed an increasing trend before continuously declining.

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