Microtubule remodeling by the innate immune factor Trim69 compromises dynein-dependent migration of HIV virion cores toward the nucleus.

Proc Natl Acad Sci U S A · 2025 · PMC12541436 · PMID 41066114

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did not reach statistical significanceno p-value reported

Interestingly, deletion of Trim69 also increased, albeit to a lower extent that did not reach statistical significance (by 1.5-fold), the susceptibility of cells to infection in the absence of IFN stimulation.

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