SUN-717 Low Penetrance of Hypophosphatasia in Asymptomatic Individuals Carrying Heterozygous ALPL Variants

J Endocr Soc · 2025 · PMC12544149

Europe PMC

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showed a trendno p-value reported

Kaplan-Meier Survival curve analysis showed a trend to earlier mobility impairment in the ALPL+ group whereas there was no significant difference in disease burden such as arthritis and fatigue.

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