The addition of GDF-15 to model 0 improved C-statistics for predicting 1-, 2-, and 3-year risk of CKD progression at borderline significance (95% CI: −0.001 to 0.02, 95% CI: −0.001 to 0.01 and 95% CI: −0.001 to 0.01 at 1, 2, and 3 years respectively) ( Table 3 ).
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GDF-15 and uEGF Independently Associate With CKD Progression in Children.
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27 However, after adjustment for cardiovascular and age-related risk factors the association was only weakly significant.