5E, F ] and showed a trend towards improvement at D30 which became significant at D58 in the BZ in the PDGF-AB group [Fig. 5G ].
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Platelet derived growth factor-AB modulates post-infarct myocardium leading to extended improvement in cardiac function.
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Similarly, for CFR, the control group showed a decreasing trend from D0 to D30, which became statistically significant on D60, whilst CFR remained stable from D0 to D60 for the PDGF-AB group [Fig. 3C ], thus showing PDGF-AB preserves blood flow through the entire coronary tree due to maintained microcirculatory function.