RANKL and CSF-1 are elevated in periovulatory follicular fluid of BRCA1 mutation carriers and increase proinflammatory signaling in fallopian tube epithelial cells.

Neoplasia · 2025 · PMC12546688 · PMID 41067178

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did not reach statistical significanceno p-value reported

RANKL- and CSF-1-induced increased ISG15 levels were decreased by pre-treatment with BAY11-7082, an NFκB inhibitor that inhibits IκBα phosphorylation; however, this did not reach statistical significance.

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