Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci.

Nat Commun · 2025 · PMC12546916 · PMID 41125582

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closest p · 1.0× alpha

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boldest claim

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nominally significantP < 0.05actually significant

We provided detailed RegulomeDB annotations in relevant cell types (e.g., hematopoietic multipotent progenitor cells, CD34+ hematopoietic progenitor cells, any primary B-cell, lymphoblastoid cell lines from 1000 Genomes [i.e., GM19238], K562, NAMALWA, BLaER1) for: (a) all index variants; and (b) credible set variants with nominally significant ( P < 0.05) functional probability scores.

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