Air pollution modulates brown adipose tissue function through epigenetic regulation by HDAC9 and KDM2B.

For each overlap, the hypergeometric test was applied, and all overlaps were found to be highly significant ( Supplemental Figure 7B ; hypergeometric test P values from proximal to distal bins, DMRs: P ≈ 7.7 × 10 –17 , P ≈ 2.5 × 10 –33 , P ≈ 1.8 × 10 –16 , P ≈ 5.1 × 10 –13 ; DARs: P ≈ 4.1 × 10 –47 , P ≈ 1.3 × 10 –64 , P ≈ 1.2 × 10 –33 , P ≈ 7.9 × 10 –36 ).

also in 132,142 other papers

In brain and heart, 18 F-fluorodeoxyglucose (FDG) uptake showed a trend to lower levels in PM 2.5 -exposed mice, while uptake in liver, skeletal muscle, and white adipose tissue (WAT) was found to be comparable to control mice ( Figure 1A ).

also in 53,322 other papers