There was a clear trend of lower viral titers in RVFVmiR-142-infected mice at 2 and 3 dpi than that in RVFVmiR-MM-infected mice; in particular, there was no detectable viral RNA in the serum, spleen, and PLN until 3 dpi, indicating better viral suppression in these tissues at early times, likely due to higher levels of miR-142 in these tissues.
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Limiting viral replication in hematopoietic cells delays Rift Valley fever virus disease progression in C57BL/6 mice.
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