Contrary to prior findings, LDLr −/− /MD-1 −/− mice exhibited progressive weight gain, with no significant difference compared to LDLr −/− /MD-1 +/− mice, although the latter showed a trend toward a plateau (Fig. 1 a, upper).
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Enhanced lymphocyte infiltration in the liver of LDL receptor and Myeloid Differentiation 1 double knockout mice on high fat diet.
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