The Impact of Bulbar and Upper Motor Neuron Involvement on Oculomotor Movement in Amyotrophic Lateral Sclerosis.

Cognitive assessments showed no significant differences between ALS patients and HCs, although ALS patients exhibited lower cognitive performance on the ECAS, which did not reach statistical significance ( T = 1.303, p = 0.197). 3.1 Comparison Between ALS Patients and HCs In the eye movement tasks, ALS patients demonstrated longer reaction time in the anti‐saccade task (357.48 ± 61.28 ms vs. 316.10 ± 52.70 ms, T = 2.909, p = 0.005) (Table 2 ).

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