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Association between the Dutch Obesogenic Built-environmental CharacterisTics (OBCT) index and 14-year cardiovascular disease incidence: a population-based cohort study of 4.4 million adults.

Lancet Reg Health Eur · 2025 · PMC12550154 · PMID 41142660

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Adherence to physical activity guidelines, and dietary behaviour mediated 13.3% of the association between the OBCT index and waist circumference, though this finding did not reach statistical significance. 22 Guo et al. found that behaviours such as diet, smoking, and alcohol consumption accounted for only about 3% of the cross-sectional association between obesogenic environments and CVD. 20 They also noted that these behaviours and cardiometabolic risk factors might act through separate pathways.

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