Barely Significant
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Real-world comparative effectiveness of first-line abemaciclib versus palbociclib in HR+/HER2- metastatic breast cancer: A propensity-matched retrospective analysis.

Breast · 2025 · PMC12550314 · PMID 41092644

1
hedged sentence
0.2700
closest p · 5.4× alpha
0.2700
boldest claim

The sentences

did not reach statistical significanceP = 0.27not close (p > 0.1)
3 , Table 2 , and eTable 8 ) All-cause hospitalizations were slightly less frequent in the abemaciclib group (cumulative probability: 13.8 % vs 20.2 %, with risk ratio: 0.68, 95 % CI: 0.61–0.77), though the difference did not reach statistical significance based on hazard ratio analysis (HR 0.93, 95 % CI 0.81–1.06; P = 0.27).

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