Identifying therapeutic targets for allergic asthma through atopic dermatitis-associated genetic mechanisms.

J Allergy Clin Immunol Glob · 2025 · PMC12552950 · PMID 41142054

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highly significantno p-value reported

For IL4R, all 5 MR methods yielded consistent and highly significant inverse associations with AA.

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did not reach statistical significanceno p-value reported

The Steiger directionality test provided evidence for the correct causal direction from AD to AA, but P = .17 did not reach statistical significance (see Table E4 in the Online Repository).

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