Efficacy of TDF, TAF, TMF, and TDF-to-TAF switch in chronic hepatitis B: a network meta-analysis.

However, the direct comparison with TAF did not reach statistical significance (OR = 0.11, 95% CI−0.14–0.37), and all TMF studies were conducted in Chinese populations with genotypes B/C, used a single manufacturer’s formulation, and had limited follow-up (92.86% ≤48 weeks, maximum 96 weeks).

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