Barely Significant
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Gut Butyrate and Blood Pressure: Insights From Recent Clinical Trials.

J Am Heart Assoc · 2025 · PMC12553433 · PMID 40736117

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9 In contrast, in Hogue et al.'s study, the 80 mmol/L butyrate enema group had significantly lower daytime SBP compared with the control group (132.9±12.64 versus 137.5±13.46 mm Hg, P =0.034), whereas in 24‐hour SBP (129.8±14.07 versus 133.8±12.31 mm Hg, P =0.054) or nighttime SBP (116.2±10.88 versus 123.2±13.56 mm Hg, p =0.262), the change in SBP did not reach statistical significance.

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