Impact of sarcopenia and frailty on outcomes of patients with sepsis or septic shock: a systematic review and meta-analysis.

Impact of sarcopenia on duration of mechanical ventilation Among three studies totaling 790 patients, sarcopenic individuals required an average of 0.99 more days of mechanical ventilation than non-sarcopenic patients, a difference that approached but did not reach statistical significance (WMD 0.99 days, 95% CI –0.003 to 1.99; z = 1.955, p = 0.051) ( Figure 8 ).

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Frailty, by contrast, demonstrated a nonsignificant trend toward increased mortality and length of hospital stay but was associated with a nearly one-day longer ICU admission in the two large cohorts available for that outcome.

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