Real-world multicenter analysis of CPX-351 efficacy in patients aged less than 60 years with secondary acute myeloid leukemia.

Blood Cancer J · 2025 · PMC12554896 · PMID 41139766

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

a nonsignificant trendp = 0.07so close (0.05 < p ≤ 0.1)

In multivariable analysis, TP53 (HR 3.1, 95% CI 1.1–9.0; p = 0.038) and HSCT in first CR (HR 0.12, 95% CI 0.06–0.3; p < 0.001) retained independent significance, whereas CK showed only a nonsignificant trend (HR 1.9, 95% CI 0.9–3.7; p = 0.07).

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did not reach statistical significanceno p-value reported

Other factors did not reach statistical significance (Supplementary Table S12 ).

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