QTc prolongation and torsades de pointes (TdP) in individuals undergoing methadone maintenance treatment (MMT): A systematic review and meta-analysis.

Medicine (Baltimore) · 2025 · PMC12558210 · PMID 41137322

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significanceP = .08so close (0.05 < p ≤ 0.1)

When the Pearson study was excluded, the pooled incidence decreased to 2% (95% CI: 0–5%), although this result did not reach statistical significance ( P = .08).

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