Assessing the efficacy and safety of pentoxifylline in preventing chemotherapy-induced peripheral neuropathy and mucositis in breast cancer patients.

Subgroup analysis based on the taxane regimen (weekly paclitaxel, dose-dense paclitaxel, and docetaxel) showed that the PTX-treated patients exhibited numerically lower incidences of grade 2 or higher neuropathy compared to controls, but these differences did not reach statistical significance ( P > 0.05, Supplementary Table S2 ).

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