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Evaluating the Neuroprotective and Acetylcholinesterase Inhibitory Properties of Four Calcineurin Inhibitor Drugs: Tacrolimus, Pimecrolimus, Cyclosporin A, and Voclosporin.

Mol Neurobiol · 2025 · PMC12559140 · PMID 40952625

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Among these, Voc exhibited a numerically greater reduction in AChE activity (96.3 ± 2.3%AChE activity); however, this difference did not reach statistical significance when compared to the other CNIs (Fig. 4 ).

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