Barely Significant
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Formulation and Optimization of a <i>Melissa officinalis</i>-Loaded Nanoemulgel for Anti-Inflammatory Therapy Using Design of Experiments (DoE).

Gels · 2025 · PMC12562900 · PMID 41149381

3
hedged sentences
0.0760
closest p · 1.5× alpha
0.0760
boldest claim

The sentences

did not reach statistical significancep = 0.076so close (0.05 < p ≤ 0.1)
Although the M-NG group consistently outperformed the standard, the difference did not reach statistical significance at this time point ( p = 0.076).

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highly significantno p-value reported
Individual terms for Tween 80 ( p = 0.0047) and homogenization time ( p = 0.0022) were also highly significant.

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marginally significantno p-value reported
The quadratic term for Tween 80 ( p = 0.0481) was marginally significant, suggesting a non-linear influence.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.