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Proteomic Profiling of Cardiomyocytes Revealed Potential Radioprotective Effects of Different Resveratrol Pretreatment Regimens.

Int J Mol Sci · 2025 · PMC12563971 · PMID 41155513

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Irradiation with 2 Gy slightly increased the number of cells undergoing apoptosis, which was not reduced by a one-day resveratrol pretreatment; however, the differences did not reach statistical significance (it should be noted that cardiomyocytes are generally resistant to radiation-induced apoptosis and we did not observe a statistically significant increase in the number of apoptotic cells even after a higher dose of 4 Gy).

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