Benzo[<i>d</i>]imidazole-Naphthalen-Arylmethanone Regioisomers as CB<sub>1</sub> Ligands: Evaluation of Agonism via an Indirect Cytotoxicity-Based Approach.

Int J Mol Sci · 2025 · PMC12564498 · PMID 41155283

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a clear trendno p-value reported

Halogen Identity and Position on the Benzo[ d ]imidazole Core A clear trend is observed across the set: a fluorine atom enhances CB 1 recognition, while chlorine generally depresses CB 1 and modestly biases CB 2 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Benzo[&lt;i&gt;d&lt;/i&gt;]imidazole-Naphthalen-Arylmethanone Regioisomers as CB&lt;sub&gt;1&lt;/sub&gt; Ligands: Evaluation of Agonism via an Indirect Cytotoxicity-Based Approach.

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Benzo[<i>d</i>]imidazole-Naphthalen-Arylmethanone Regioisomers as CB<sub>1</sub> Ligands: Evaluation of Agonism via an Indirect Cytotoxicity-Based Approach.