Barely Significant
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The Emerging Role of Magnesium in Preventing Acute Kidney Disease During Concurrent Chemoradiotherapy in Head and Neck Cancer.

Cancers (Basel) · 2025 · PMC12564704 · PMID 41154367

2
hedged sentences
0.0500
closest p · 1.0× alpha
0.0500
boldest claim

The sentences

did not reach statistical significancep ≥ 0.05actually significant
All other evaluated categorical variables, including insulin use, proton pump inhibitors, systemic corticosteroids, acetylsalicylic acid, oral antidiabetic agents, alcohol consumption (Potus), opioid analgesics, β-blockers, calcium antagonists, diuretics, diabetes mellitus, current smoking status, and female sex, did not reach statistical significance ( p ≥ 0.05), indicating no measurable association with AKD in this cohort.

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a possible trendno p-value reported
Baseline body weight and estimated glomerular filtration rate at cycle 1 (GFR_C1) demonstrated borderline associations with AKD ( p = 0.06 for both), implying a possible trend toward higher risk in patients with greater body mass or lower baseline kidney function reserve.

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