We found a positive trend between t1⁄2 and creatinine at 24 (ρ = 0.176, p = 0.07) and 72 h (ρ = 0.223, p = 0.053), although it did not reach statistical significance.
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Pharmacokinetics and Monitoring of Methotrexate in Adults with Acute Lymphoblastic Leukaemia: A 10-Year Follow-Up at an Italian Centre.
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