Although a trend toward a stronger effect was observed among patients with multivessel coronary disease, this interaction did not reach statistical significance, but it raises the possibility of a synergistic relationship between hyperuricemia and advanced atherosclerosis that merits further investigation.
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Prognostic Value of the NAPLES Score and Serum Uric Acid in Chronic Coronary Syndrome: Evidence from Time-Dependent ROC and Time-Varying Hazard Ratio Analyses.
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