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Prognostic Value of the NAPLES Score and Serum Uric Acid in Chronic Coronary Syndrome: Evidence from Time-Dependent ROC and Time-Varying Hazard Ratio Analyses.

J Clin Med · 2025 · PMC12565530 · PMID 41156285

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Although a trend toward a stronger effect was observed among patients with multivessel coronary disease, this interaction did not reach statistical significance, but it raises the possibility of a synergistic relationship between hyperuricemia and advanced atherosclerosis that merits further investigation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.