Efficacy and Safety of Intraosseous Versus Intravenous Antibiotic in Primary and Revision Total Joint Arthroplasty: A Systematic Review and Meta-Analysis.

Medicina (Kaunas) · 2025 · PMC12565870 · PMID 41155737

Europe PMC DOI

hedged sentence

0.2300

closest p · 4.6× alpha

0.2300

boldest claim

The sentences

did not reach statistical significancep = 0.23not close (p > 0.1)

In meta-analyses evaluating PJI mitigation, a significant reduction in PJI rates was observed in primary TKA; however, when revision TKA cases were included, the overall effect did not reach statistical significance ( p = 0.23).

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